GABA 500mg + Vitamin B6 - 120 vcaps - Osavi
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GABA 500mg + Vitamin B6 - 120 vcaps - Osavi
GABA 500mg + Vitamin B6 - 120 vcaps - Osavi
Learn more about this product. A dietary supplement in hard capsule form containing GABA and vitamin B6. Gamma-aminobutyric acid (GABA) acts as a neurotransmitter in the body. Vitamin B6 helps the nervous system function properly. Can't sleep, feeling anxious, and unable to cope with stressful situations? Perhaps you are lacking gamma-aminobutyric acid. It is responsible for relaxation and reducing anxiety. Try GABA with vitamin B6 and check how these substances affect your nervous system and sleep. GABA (gamma-aminobutyric acid, γ-aminobutyric acid) belongs to the group of non-protein amino acids and is one of the most important inhibitory neurotransmitters in the central nervous system (CNS). It is responsible for, among other things, relieving nervous tension and is produced naturally in the body. GABA (i.e., a relaxation-promoting, inhibitory neurotransmitter) is produced directly from glutamate (a stimulatory neurotransmitter). Both of these neurotransmitters should be balanced with each other. Gamma-aminobutyric acid is formed in the brain by converting glucose to glutamate, and then glutamate to GABA. Glutamate decarboxylase (GAD) is the main enzyme required for the production of GABA from glutamate. This enzyme, in turn, requires vitamin B6 to function. GABA is considered a natural relaxation agent; it is responsible for promoting relaxation and reducing anxiety, and it increases resistance to stressful conditions. It has been proven that gamma-aminobutyric acid improves sleep quality. On the other hand, vitamin B6 – which helps with optimal nervous system functioning and the maintenance of proper psychological functions, and also contributes to the reduction of tiredness and fatigue – is important for the synthesis of many neurotransmitters, including GABA. It has been proven that pyridoxine supplementation reduces anxiety and depressed mood, and also strengthens visual surround suppression (i.e., the ability to turn off background visual noise while being able to detect a target that differs slightly from the immediate background). This suggests that high-dose vitamin B6 supplementation may enhance the neural effects of inhibitory GABA. Taking GABA as part of a diet helps improve overall mental balance. The capacity for gamma-aminobutyric acid production is demonstrated by, for example, specific strains of lactic acid bacteria. Therefore, it is worth reaching for dairy products and silages. Among plant-based products that are good sources of GABA, one can mention, for example, brown rice germ, grain germ, and spinach. Potatoes, sweet potatoes, and cabbage have lower concentrations of this nutrient. On the other hand, vitamin B6 is found in fish, organ meats (e.g., beef liver), potatoes, and other starchy vegetables. Low levels of vitamin B6 can lead to cognitive decline and depressed mood. A deficiency of γ-aminobutyric acid contributes to, among other things, anxiety and insomnia. Therefore, introducing appropriate supplementation can help maintain the body's harmony. GABA 500 mg + Vitamin B6 is a safe supplement that contains natural extracts and features a so-called "clean label," which is proof that it does not contain unnecessary additives. This allows even the most demanding customers to consume the product without fear. One capsule corresponds to the recommended daily dose: 500 mg of GABA and 2 mg of vitamin B6 (143% NRV). The OSAVI supplement is best taken in the evening, after a meal. Why might someone benefit from GABA 500 mg + Vitamin B6 supplementation? - Vitamin B6 contributes to the normal functioning of the nervous system. - Vitamin B6 contributes to normal psychological functioning. - Vitamin B6 contributes to the reduction of tiredness and fatigue. - GABA acts as a neurotransmitter in the body. What is special about GABA 500 mg + Vitamin B6 capsules? - Contains 500 mg of GABA and vitamin B6 (143% NRV), which is important for the nervous system. - Clean label - no unnecessary additives. - Suitable for vegetarians and vegans. - Free from gluten, lactose, soy, and GMOs. - Packaging made from BioPET (30% of the plastic is derived from sugarcane). [1] Jewett BE, Sharma S. (2022). Physiology, GABA. [Updated 2022 Jul 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. Retrieved 27.01.2023 from https://www.ncbi.nlm.nih.gov/books/NBK513311/. [2] Siegel GJ. et al. (1999) Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition. GABA Synthesis, Uptake, and Release. Philadelphia: Lippincott-Raven. https://www.ncbi.nlm.nih.gov/books/NBK27979/. [3] Abdou, A.M. et al. (2006). Relaxation and immunity enhancement effects of γ-Aminobutyric acid (GABA) administration in humans. BioFactors, 26: 201-208. https://doi.org/10.1002/biof.5520260305. [4] Byun JI. et al. (2018). Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial. J Clin Neurol., 14(3):291-295. doi: 10.3988/jcn.2018.14.3.291. Epub 2018 Apr 27. PMID: 29856155; PMCID: PMC6031986. [5] Field, D. T., et al. (2022). High-dose vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression. Human Psychopharmacology, 37(6), e2852. https://doi.org/10.1002/hup.2852 [6] Cui, Y. et al. (2020). Production of Gamma-Aminobutyric Acid from Lactic Acid Bacteria: A Systematic Review. International Journal of Molecular Sciences, 21(3), 995. https://doi.org/10.3390/ijms21030995. [7] Briguglio M. et al. (2018). Dietary Neurotransmitters: A Narrative Review on Current Knowledge. Nutrients; 10(5):591. https://doi.org/10.3390/nu10050591. [8] Vitamin B6. Fact Sheet for Health Professionals. National Institutes of Health. Office of Dietary Supplements. Retrieved 27.01.2023 from https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/
Ingredients
| Amount per 1 serving | NRV %* |
|---|---|
| Energy value – 10 kJ / 2 kcal | * |
| Fat – 0 g | * |
| of which saturates – 0 g | * |
| of which unsaturates – 0 g | * |
| Carbohydrates – 0 g | * |
| of which sugars – 0 g | * |
| of which polyols – 0 g | * |
| of which starch – 0 g | * |
| Fiber – 0.2 g | * |
| Protein – 0.5 g | * |
| Salt – 0 g | * |
| GABA (gamma-aminobutyric acid) – 500 mg | * |
| Vitamin B6 (pyridoxine hydrochloride) – 2 mg | 143% |
* NRV – Nutrient Reference Value for an adult.
Excipients
No additional excipients.
Usage
Recommended daily intake: 1 capsule in the evening, after a meal.
Warnings
- Do not use if you are allergic to any of the product's ingredients.
- Do not exceed the stated recommended daily dose.
- Dietary supplements should not be used as a substitute for a balanced diet.
- Keep out of reach of children.
- Recommended for use by individuals 18 years of age or older.
- Consult a physician before use if pregnant, nursing, or if you have a medical condition.
Storage conditions
Store in a tightly closed container, in a dry, cool place (up to 25 °C), out of the reach of children, away from direct sunlight.
Manufacturer: Osavi
Country: Latvia
Delivery
EU countries – delivery to DPD parcel lockers, free on orders of €99 or more:
- Ireland – €10.99
- Netherlands – €7.99
- Belgium – €6.99
- Luxembourg – €8.99
- Germany – €6.99
- Austria – €8.99
- France – €9.99
- Denmark – €11.99
- Sweden – 120 SEK, free on orders of 1 099 SEK or more
- Finland – €10.99
- Poland – €3.99, free on orders of €49 or more
- Czechia – €6.99
- Slovakia – €6.99
- Slovenia – €9.99
- Portugal – €9.99
Baltic states – delivery to parcel lockers:
- Lithuania (LP Express) – €2.89, free on orders of €39 or more (except the Curonian Spit)
- Latvia (Unisend) – €3.79, free on orders of €49 or more
- Estonia (Unisend) – €3.89, free on orders of €49 or more
- Parcels must be collected from the parcel locker within 72 hours.
Delivery time – 5–8 business days.
Return policy
The Buyer may not return the following goods:
• Medicinal products (prescription and non-prescription).
• Reimbursable medical devices.
• Goods that the Buyer has used or damaged, whose packaging the Buyer has damaged, or which have lost their commercial appearance due to other actions of the Buyer, as well as incomplete goods (e.g. missing parts, no instructions for use or warranty card).
• Other goods whose return the seller may refuse under EU legislation.
Goods are considered of proper quality if:
• The expiry date has not passed.
• They contain no prohibited substances.
• They were stored under proper conditions until handed over to the Buyer.
• The goods are not mechanically damaged and their packaging is intact.
Conditions for returned or exchanged goods
Goods of proper quality that are returned or exchanged must be:
• Returned within 14 days of receiving the order.
• Undamaged and must not have lost their commercial appearance (labels not removed or damaged, protective films not torn off, etc.).
• Unused.
Important:
The Buyer pays the return shipping costs. Shipping costs – both for delivering the goods to the Buyer and for returning them – are not refunded.
Goods must be returned:
• In the original, unopened packaging.
• Complete, exactly as received.
• Together with the proof of purchase, the warranty card (if issued), instructions for use and other accessories.
The Seller has the right to refuse to accept or exchange the goods and to refuse a refund if:
• The packaging has been opened.
• The goods are incomplete.
• The goods are damaged or defective.
• The goods are not properly packed.